2018 session 1 ================ Activation of Sonic hedgehog signaling in ventricular cardiomyocytes exerts cardioprotection -------------------------------------------------------------------------------------------- against ischemia reperfusion injuries ------------------------------------- Statistics. Presented numerical data are Mean +/- standard error of mean (SEM). Results were considered significant if p , 0.05, with one-way, two-tailed Analysis of Variance (ANOVA) with Bonferroni post-test. Further details on methods are included in Supplementary material online. Interactions Between beta-Catenin and Transforming Growth Factor-beta Signaling Pathways ----------------------------------------------------------------------------------------- Mediate Epithelial-Mesenchymal Transition and[...] --------------------------------------------------- Statistical Analysis : data are shown as means ± S.E.; n is the number of observations. We used z-tests to determine whether the ratiometric data (i.e. normalized against control) are different from control. p < 0.05 was considered significant. The severity of NAFLD is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota ---------------------------------------------------------------------------------------------------------------- Statistics : Quantitative variables were expressed as median with 1st and 3rd quartiles into brackets. Raw observation counts in taxa summary plots were normalized by calculating relative abundance. Qualitative variables were compared using the Fisher's exact test and quantitative variable using the Mann Whitney test. A p value less than 0.05 was considered statistically significant. Statistical analyses were performed using SPSS version 18.0 software (IBM, Armonk, NY, USA).! Melanoma antigen A12 regulates cell cycle via tumor suppressor p21 expression ----------------------------------------------------------------------------- [...]with data expressed as the ratio of values for cells transfected with MAGE-A12 to values for the control siRNAs (mean ± SD; n = 3). *** p < 0.001 by t-test. Mild palmitate treatment increases mitochondrial mass but does not affect EA.hy926 endothelial cells viability -------------------------------------------------------------------------------------------------------------- Data are shown as means of ratios of treatment to control values ± SD, for the number of replicates indicated in figure legends. Confidence intervals for geometric means of ratios between treatment and appropriate controls were found using the t method for paired design (TTEST procedure) [27] with 95% confidence level. Associated p-values for the null hypothesis that the ratio equals one are also reported. Functional diversity and properties of multiple xylanases from Penicillium oxalicum GZ-2 ---------------------------------------------------------------------------------------- The transcript level of xyn11A was significantly higher (P < 0.05) than that of the other xylanase genes. pH-responsive lipid nanocapsules for enhanced cellular uptake ------------------------------------------------------------- Results (n=4) are expressed as mean measure ± standard deviation. Kruskal-Wallis, post-hoc Dunn\u2019s, correction Hochberg. For statistical analysis of size, BLK LNC was used as reference, ***p<0.001 , ** p< 0.01, *p<0.05. Characterisation of adipocyte-derived extracellular vesicle subtypes[...] ------------------------------------------------------------------------- All statistical procedures were carried out under the R v3.1.1 environment [31] using base packages developed by the PAPPSO platform (http://pappso.inra.fr/index.php?). Only peptides present in less than 2% of the sample and belonging to multiple proteins were removed. Changes in protein abundance were detected by analysis of variance. For both methods (XIC and SC), proteins were considered significant when the adjusted p value was < 0.05. The protein content of each EV pellet normalised to the protein content of the original productive 3T3-L1 adipocytes is presented. n=3-9 independent EVpreparations, **p<0.01, (Mann-Whitney rank test). 3T3-L1 adipocytes secrete substantiallymore sEVs than lEVs in serum-deprived conditions. n = 4 biological samples for lEVs and for sEVs, *p < 0.05 (Mann\u2013Whitney rank test).